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Up−to−date pharmacological and surgical methods of chronic heart failure treatment are described. A protocol of supporting therapy and drugs which should be avoided in this disease are cited.

Risk factors of atherosclerosis development are described, a number of theories explaining atherosclerotic changes appearance in the coronary arteries are analyzed critically. The role of endothelial dysfunction in progress and exacerbation of cardiovascular diseases is emphasized. Contemporary approaches to atherosclerosis treatment are discussed.

Electro− and echocardiography parameters of the changes in the course of treatment with streptase of the patients with acute uncomplicated myocardial infraction were studied. Positive dynamics of ECG and EchoCG changes, reduction of the heart rate and prolongation of electric ventricular systole already on the first day after the fibrinolytic infusion administration were noted. Streptase therapy improved systolic function of the left ventricle and prevented post−infarction changes in the structure and function of the myocardium.

Significance of rehabilitation in contemporary medicine is shown. The principles of the suggested original system for rehabilitation primarily of the patients with chronic somatic diseases are formulated and described.

The importance of timely revealing and diagnosis of depressions at the primary level of medical care as well as the tactics of cooperation of family physicians and psychiatrists at the primary level are shown. The information about main signs and diagnostic criteria of depressions is presented. The principles of therapy and prevention of depressions are discussed. Main classes of drugs used in treatment for depressive states are characterized.

The authors' opinion about some possible mechanisms of psychotherapy, in particular in complex treatment of cancer pathology, is given. The conditions necessary for effective influence of a psychotherapist on the course of reparative processes at treatment of patients with malignant tumors are described. Clinical observations of one of the authors are analyzed.

Various types of family trouble associated with mental health of children are featured. A practical classification of family trouble is suggested. A number of regularities, which reflect correlation of the suggested classification and mental health of children, is suggested.

The data about the use of monomole gadolinium−containing contrast material Gadovist 1.0 at high dose magnetic resonance imaging are described. Its advantages vs 0.5−mole MRI contrast media in diagnosis of stroke, tumors, and demyelinizing diseases of the brain for obtaining first passage images, revealing small injuries and other lesions of the brain and spinal cord are shown.

Urgency of the problem of neurological pathology forming in the persons taking hand−made ephedrine−like psychostimulators is shown. The possibility to use botulotoxin to correct the myodystonic manifestations which has developed in these patients is validated.

Contemporary ideas about the pathogenesis, clinical manifestations, diagnosis and principles of treatment of antiphospholipid syndrome are presented. The findings of the original research are reported. A case of "catastrophic" antiphospholipid syndrome is described.

The characteristics of sex−role behavior of women with various types of organic personality disorders at sociogenic, behavioral and biogenic levels has been established. Dependence of symptom−complex masculinity/femininity on the type of personality disorder and position of each type in sex−role space is shown.

Five hundred women having extra−marital liaison were examined using a special questionnaire. The obtained data were used to reveal the causes, conditions of development and character of conjugal infidelity as well as their interrelation with spouse deadaptation.

Disorders of somatopsychosexual development were revealed in children and teen−agers with epilepsy. Their pathological influence on personality development is shown. The author concludes about the necessity to use correction of these disturbances in complex treatment of the patients.

Updated data about lactation function in puerperas and factors causing its disturbances are described. The importance of breast feeding for the child and the mother is emphasized.

Capabilities of ultrasound study of provisional organs of the fetus in intrauterine infection are featured. Bacterial, virus and mixed infection are shown to be characterized by ultrasound signs which can be visualized prenatally.

Informativity of various x−ray techniques as well as CT and MRI in diagnosis of primary mediastinal tumors, including thymus tumors and cysts is compared. The indications to the use of different methods of morphological verification of the tumors has been determined. The possibility to create a diagnostic algorithm is shown.

A method of prevention and treatment of intra−abdominal abscesses based on active drainage of the abdominal cavity by introduction through the canal of a tube probe of multicomponent drugs on hydrophilic base is suggested. High efficacy and reasonability of wide use of this method in clinical practice are shown.

Modern principles of surgery for deep burns of the face and neck are stated. The use of the original new surgical tactic technologies aimed at achievement of anatomical, functional and esthetic results at the stage of acute injury is substantiated.

The experience of treatment of 2996 patients with neuromuscular diseases of different origin and localization has been generalized. Classification of types of extremity instability is presented, tendomuscular plastics was validated experimentally and clinically. The necessity of complex approach to treatment of this category of patients, which includes both conservative and operative measures, psychological, and social adaptation of the patients, has been proven.

The principles, technical characteristics and diagnostic capabilities of contemporary biopsy morphology studies are shown. The author concludes about decisive importance of the findings of pathohistological method at various forms of traumas and oncological orthopedic pathology. Methodological approaches and optimization of biopsy morphological diagnosis are discussed.

Methods of diagnosis and treatment of pleurisy, which complicates the course of tumor process, are described to work out optimum therapeutic tactics. Successful treatment of the tumor pleurisy is shown to allow to administer more active treatment of the basic disease facilitating improvement of the quality of life of the patients.

High efficacy of complex treatment of breast cancer with the use of selective intra−arterial and endolymphatic polychemotherapy vs other methods is shown. The results of the use of the developed in Donetsk Regional Anti−tumor Center techniques of adjuvant and neoadjuvant chemoradiation therapy and surgery aimed at improvement of the results of treatment and quality of life of the patients are presented.

Main problems of diagnosis and treatment of kidney angiomyolipoma (AML) are featured. Main criteria of kidney AML are evaluated basing on modern medical visualization techniques (ultrasound, CT, MRI). Classification of the tumors of this type according to preferable methods of treatment depending on the size and biological behavior of the tumor is suggested.

The experience of sigmoid colon use in forming orthoptic urinary bladder after radical cystectomy for cancer is reported. Presence of dolichosigmoid is considered an indication to neocystoplasty. The necessity of prevention of ascending reflux pyelonephritis at formation of orthoptic neocyst is emphasized. Two variants of the original surgical techniques are described.

The results of testing of two biophysical methods of etiological express diagnosis of drug disease based on evaluation of the difference in the level of ultrasound absorption by erythrocytes and their sedimentation in control and experimental samples are presented. Contraindications to skin tests are cited, difficulties of etiological diagnosis of drug disease with the use of specific immunological tests are described.

Biological properties of Chlamydia and the problems of epidemiology of Chlamydia infection are featured. Its high frequency in many countries including Ukraine and considerable pathogenic influence on the health of men, women, and children are shown.

Current ideas about psychotherapy oriented on the body are highlighted. The history, theoretical, and methodological approaches to treatment of the mind through the changes in the body are discussed. Diagnostic and therapeutic techniques used at therapeutic interrelations are described.

Current approaches to correction of endothelial dysfunction in cardiovascular diseases are discussed. The mechanisms of action of drugs, which improve the functional state of the endothelium, interrelation between clinical efficacy of the drugs and their capability to reduce endothelium dysfunction are shown. It is concluded that the data about the role of endothelium dysfunction determine the prospects of therapeutic methods based on improvement of the functional state of the endothelium.