ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 22., Iss. 1, 2016, P. 42−48.
EFFECTS OF INFECTIOUS FACTORS ON PERINATAL MORBIDITY AND MORTALITY IN PRETERM INFANTS
Kharkiv Regional Clinical Perinatal Center, Ukraine
Pregnancy in women with infectious pathology develops in specific environment and has a large number of perinatal complications, reduction of which is an urgent obstetric problem. Appearance of new diagnostic capabilities allows to study the etiological factors in detail and provides a new approach to definition of the pathogenetic mechanisms of perinatal complications, especially in the premature newborns and preterm rupture of the membranes. The aim of the work was to develop pathogenetic methods of treatment and prevention of infectious lesions in the fetus and premature newborns. It was found that perinatal complications, which are usually caused by infectious, immunological disorders, formation of endothelial dysfunction. The complex of measures aimed at optimizing the management of pregnancy, which can improve the course of the gestation period, reduce the number of perinatal complications for both the mother and the newborn, by normalizing the disturbed parts of the regulatory mechanisms, endothelial system and immunological homeostasis, which is achieved by carrying out ozone therapy and immune correction, was suggested.
Key words: perinatal pathology, premature birth, immunotherapy, medical ozone.