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№2' 2015


International Medical Journal, Vol. 21., Iss. 2, 2015, P. 66−70.


Florikian V. A.

Kharkiv Medical Academy of Postgraduate Education, Ukraine

The frequency and occurrence of traumatic brain injury in Ukraine ranges from 2.8 to 5.4 cases per 1000. After 2−4 years in 80 % of them different in structure and degree posttraumatic cerebral pathology, especially venous discirculatory is observed. Clinicians are searching for medical and drug−free methods of treating this pathology. It is of interest to study the effectiveness of Diosmin series drug on clinical manifestations of cerebral venous encephalopathy in patients in the late period of closed craniocerebral trauma and treatment of patients with the same pathology by complex method −− Diosmin and magnetophoresis with 10 % solution of bromine at the level of C8−Th2. The study was conducted on 72 patients with cerebral discirculatory venous pathology in late period of closed craniocerebral injury (CCI). The patients were divided into two groups. Group 1 (controls) consisted of 34 patients (47.2 %), who were administered Diosmin 600 mg a day, in the morning 30 minutes before breakfast for 30 days. Group 2 (main) included 38 patients (52.8 %), who had medical treatment, consisting of Diosmin 600 mg, and methods of physiotherapy magnetophoresis with 10 % solution of bromine at the level of C8−Th2. All patients with CCI underwent a common scheme of clinical and neurological examination. To verify the violations of cerebral hemodynamics extra and transcranial Doppler method was used. The indices of central hemodynamics and cardiopulmonary reserve were calculated by the original non−invasive method. The results obtained demonstrate a positive therapeutic effect of magnetophoresis with 10 % solution of bromine and Diomin at a dose of 600 mg on hemodynamics of the pulmonary circulation and blood circulation on the whole, indicate a rather pronounced compensatory potential of central and cerebral vascular system of the patient. Unlike the patients with initial manifestations of cerebral venous pathology, the patients with venous dystonia and examined patients with severe venous disorders (group 3) did not have any improvement in aerobic performance after pathogenetic treatment performed with 600 mg of Diosmin with magnetophoresis, which indicates significant violations of compensatory opportunities of vascular system and organic changes both in cerebral vessels and pulmonary circulation.

Key words: brain injury, venous circulatory encephalopathy, diosmin, magnetophoresis with 10 % solution of bromine.

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