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№2' 2013
OBSTETRICS AND GYNECOLOGYInternational Medical Journal, Vol. 19., Iss. 2, 2013, P. 69−71.
THE FEATURES BLOOD LIPID PROFILE IN PATIENTS WITH ADENOMATOUS AND GLANDULAR ENDOMETRIAL HYPERPLASIA
Kharkiv National Medical University, Kharkiv, Ukraine
Abstract. Blood serum lipid profile was investigated in 131 women with adenomatous and glandular endometrial hyperplasia with obesity and normal body mass. It was revealed that the majority of patients with adenomatous and glandular endometrial hyperplasia demonstrated disorders of lipid blood profile characterized by dyslipoproteinemia predominantly type IIa and IIb. Dyslipoproteinemia development occurred due to increase of atherogenic classes of lipoproteids and reduction of antiatherogenic high density lipoproteids. Lipid blood spectrum in patients with endometrium hyperplasia was accompanied by disorders in lipid transport system, characteristic both for obesity and negative influence of hyperinsulinemia and ovarian hyperandrogeny. The presence or absence of metabolic syndrome based on insulin resistance manifesting by hyperinsulinemia, dyslipoporteidemia, ovarian hyperandrogeny significantly influences development of endometrial hyperplasia.
Key words: endometrial hyperplasia, dyslipoproteinemia, blood lipid profile.