ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 19., Iss. 2, 2013, P. 72−75.
ANTI-MULLER HORMONE DETECTION AND DOPPLER STUDY OF OVARY BLOOD SUPPLY IN DIAGNOSIS OF POOR OVARIAN RESPONSE SYNDROME
SI "Ukrainian Medical Center of Obstetrics, Gynecology and Reproductology of Ministry of Health of Ukraine", Kharkiv, Ukraine
Abstract. Poor ovarian response syndrome (PORS) is characterized by controlled ovarian stimulation not exceeding 3−5 preovulatory follicles by the end of the protocol. In our study we compared patients with normal response to stimulation and patients with PORS. Diagnostic value of two techniques, Doppler ultrasound of ovarian blood flow and determining blood anti−Muller hormone, was compared. Such Doppler ultrasonography parameters as resistance index and pulse index were used for quantitative interpretation of spectrum curves of blood flow velocity. Anti−Muller hormone in the blood was determined using immunoenzyme assay based on the principles of enzyme enhanced two−stage sandwich control. It was established that Doppler ultrasound parameters of ovarian blood flow were prognostically more valuable and accurate in determining PORS vs. determining blood anti−Muller hormone, yielding false−positive results in a number of cases.
Key words: anti−Muller hormone, Doppler investigation, syndrome of poor ovarian response, controlled ovarian stimulation.