Previous Next


№1' 2021


International Medical Journal, Vol. 27., Iss. 1, 2021, P. 18−22.



Voronenko O. S., Brynza M. S.

V. N. Karazin Kharkiv National University, Ukraine

In recent decades, there has been a rise of chronic heart failure mortality. Among the huge range of modern methods of this pathology treatment, the cardioresynchronizing therapy stands out, it allows the improvement of the patient's heart function, reduces clinical signs of the disease, improves well−being, as well as diminishes morbidity and mortality. The use of this method in the patients with a comorbid pathology, i.e. in those with chronic heart failure and type 2 diabetes, deserves a special attention. In order to determine the clinical characteristics of the patients who required a pacemaker implantation, we examined 203 patients who had reasonable indications for this in accordance with the ACC / ANA and ESC current recommendations. Another important criterion for inclusion into the group of implantation was considered to be the presence of comorbid Diabetes mellitus type 2. The gender and age characteristics of the surveyed population were dominated by elderly male patients. The presence of concomitant cardiovascular pathology depending on the age of patients was analyzed, which showed mostly hypertension of stage 2−3, a constant atrial fibrillation. In structure of comorbid pathology the somatic diseases, including type 2 Diabetes mellitus prevailed. Electrostimulators were implanted into the examined cohort of patients, among which 132 devices worked in DDD mode, 71 of the installed stimulators had the DDDR mode. The research results concluded that the implantation of a pacemaker became a necessary procedure for elderly patients, mostly men, with a high prevalence of cardiovascular (coronary heart disease, hypertension, persistent atrial fibrillation) and somatic pathology in the form of type 2 Diabetes mellitus.

Key words: chronic heart failure, type 2 diabetes mellitus, pacemaker implantation, clinical features, gender and age characteristics.


1. Naselennya Ukraїni za 2019 rіk. Demografіchnii shchorіchnik. Derzhavna sluzhba statistiki Ukraїni. K., 2020. 181 s. URL: PXWEB2007/ukr/publ_new1/2020/zb_nas_2019.pdf

2. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC / P. Ponikowski et al. // Eur. Heart J. 2016. № 37 (27). R. 2129−2200. doi: 10.1093/eurheartj/ehw128

3. ICD−11 for Mortality and Morbidity Statistics (Ver sion 09/2020). URL: l−m/en

4. ACC/AHA/HFSA Focused Update of the 2013 ACCF/ AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/Ameri can Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America / C. W. Yancy et al. // Circulation. 2017. № 136 (6). e137−e161. doi: 10.1161/CIR.0000000000000509

5. Rekomendatsії Asotsіatsії kardіologіv Ukraїni z dіagnostiki ta lіkuvannya khronіchnoї sertsevoїnedostatnostі. Sertseva nedostatnіst' ta komorbіdnі stani. 2017. № 1. S. 1−66.

6. The Task Force for the management of arterial hyper tension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) // Eur. Heart J. 2018. 00. R. 1−98. doi: 10.1093/eurheartj/ ehy339

7. American Diabetes Association.2020. Standards of medical care in diabetes−2020 abridged for primary care providers // Clinical Diabetes. 2020. № 38 (1). R. 10−38. URL:−as01

8. American Diabetes Association. 2019. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes−2019 // Diabetes Care. 2019. № 42 (Suppl. 1). P. 13−28. doi:10.2337/dc19−S002

9. Marx N. Neue ESC−Leitlinie 2019 "Diabetes, Prädiabe tes und kardiovaskuläre Erkrankungen": Paradigmen wechsel in der Reduktion des kardiovaskulären Risikos bei Patienten mit Diabetes mellitus // Herz. 2019. № 44 (8). R. 684−687. doi:10.1007/s00059−019−04860−8

10. Zagal'nі printsipi organіzatsії dіyal'nostі komіsіi z pitan' etiki pri lіkuval'no−profіlaktichnikh za kladakh, v yakikh provodyat'sya klіnіchnі viprobuvannya lіkars'kikh zasobіv (rekomendatsії dlya ekspertіv): posіb. / L. Kovtun ta іn. K., 2017. 45 s.

11. Standardization of adult transthoracic echocardiography reporting in agreement with recent chamber quan tification, diastolic function, and heart valve disease recommendations: an expert consensus document of the European Association of Cardiovascular Imaging / M. Galderisi et al. // Eur. Heart. J. Cardiovasc Imag ing. 2017. № 18 (12). P. 1301−1310. doi: 10.1093/ ehjci/jex244

12. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the Ameri can Society of Echocardiography and the European Association of Cardiovascular Imaging / R. M. Lang et al. // J. Am. Soc. Echocardiogr. 2015. № 28 (1). P. 1−39. doi: 10.1016/j.echo.2014.10.003

13. Lapach S. N. Statisticheskie metody v mediko−bio logicheskikh issledovaniyakh s ispol'zovaniem Excel. K.: Morion, 2000. 320 s.

14. Nasledov A. SPSS − komp'yuternyi analiz dannykh v psikhologii i sotsial'nykh naukakh. SPb.: Piter, 2007. 416 s.

15. Age standardization of rates: a new who standard. Discussion Paper Series / O. B. Ahmad et al. // EIP/ GPE/EBD World Health Organization 2001. № 31. URL:

Go on Top