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№2' 2017


International Medical Journal, Vol. 23., Iss. 2, 2017, P. 24−27.


Zhadan A. V.

Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine

Surgery for infectious endocarditis is the most important method of treatment. Studies on long−term follow−up of the patients who were performed valvular prosthesis implantation relate mainly to the occurrence of complications and repeated operations in this regard. However, assessment of clinical, instrumental and laboratory indicators associated with a fatal risk, analysis of their dynamics depending on the presence of concomitant pathology, are still relevant for practical health care. Our investigation allowed studying the long−term prognosis in 53 operated patients with infective endocarditis, as well as the factors influencing the course of the disease. The patients underwent grafting of one or two valves (aortic and mitral), mitral valve plastic surgery. During five years of observation, nine patients died, in three cases due to non−cardiac events. The analysis of clinical instrumental findings obtained at different observation times in these patients indicated that they had higher creatinine level, lower creatinine clearance level, higher content of NT−pro−BNT natriuretic peptide compared to the surviving patients. The obtained data allowed concluding that the risk of death in patients who underwent cardiac surgery for infectious endocarditis is associated with reduction in the renal function and increase in the level of NT−pro−BNT, which indicates myocardial dysfunction development.

Key words: infective endocarditis, cardiac surgery, atrial fibrillation, survival.

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