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№3' 2016


International Medical Journal, Vol. 22., Iss. 3, 2016, P. 65−67.


Yavorska V. O., Hrebeniuk H. V., Kryvchun S. A., Anisenkova V. Yu.

Kharkiv Medical Academy of Postgraduate Education
Kharkiv City Hospital № 7, Ukraine

Chronic occlusive cerebral vasculopathy (Moya−Moya disease) refers to a group of rare diseases. The mechanism of its occurrence is based on slowly progressive stenosis and obliteration of the large vessels as well as development of broadened collateral network of basal cerebral arteries. Idiopathic (congenital) and symptomatic (acquired) form of the disease are distinguished. The first symptoms manifest in the age groups from 10 to 20 years, from 30 to 40 years. The diagnosis of the disease is difficult due to the lack of pathognomonic symptoms. Its gold standard is endovascular cerebral selective angiography, a highly informative and accessible method. The clinical manifestations of this disease were investigated on a practical example to optimize diagnostic criteria. Two clinical cases of the disease are featured. These young patients presented in a state of moderate severity and in serious condition. Typical changes in the form of severe stenosis/occlusion of M1 segment of the both middle cerebral arteries with formation of multiple collaterals were found during angiography, which is typical for this disease. The patients were observed for 6 months, both on the outpatient and inpatient basis. Stable clinical effect was achieved in the patients as a result of conservative treatment.

Key words: vasculopathy, Moya−Moya disease, diagnosis, treatment.

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