International Medical Journal, Vol. 21., Iss. 2, 2015, P. 90−94.
TYPE 1 BOCAVIRUS DETECTION IN CHILDREN WITH CLINICAL MANIFESTATIONS OF ACUTE RESPIRATORY VIRAL INFECTION
P. L. Shupik National Medical Academy of Postgraduate Education, Ukraine
Acute respiratory infections are one of the most pressing problems of Ukrainian pediatrics, as they make over 90 % of all infectious diseases in children population. The studies conducted in 2011−2014 revealed a significant spread of infection with bocavirus (NBoV1) in Ukraine. It was noted that the peak of incidence in the country is in December. Virological studies to identify HBoV were conducted in a scientific laboratory of P. L. Shupik National Medical Academy of Postgraduate Education. Real−time polymerase chain reaction was used to analyze 458 samples of biological material taken from hospitalized children with acute respiratory viral infection. The results showed the presence of DNA bocavirus in 23.5 % of cases in patients aged 1−7 years. The patients with bocavirus infection most commonly present with cough, corisa, fever, difficult breathing, edema. It was established that bocavirus can affect the upper and lower airways, which is manifested by acute otitis, tonsillitis, pharyngitis, laryngotracheitis, obstructive bronchitis, pneumonia. Today one of the main methods of bocavirus detection is real−time polymerase chain reaction, which allows to quickly obtain accurate information about the etiological cause of acute respiratory viral disease and prescribe treatment.
Key words: human bocavirus, diagnosis, acute respiratory viral infections.