Previous Next

ARCHIVE

№4' 2013

INFECTIOUS DISEASES

International Medical Journal, Vol. 19., Iss. 4, 2013, P. 78−81.

ADAPTATION COMPENSATORY CAPABILITIES OF THE HUMAN BODY AT DEMODECOSIS

Dermatovenereology Hospital, Belgorod−Dnesterovsky, Odessa region; Bukovinsky State Medical University, Chernivtsi

Cortisone and insulin level, basal level of hypophyseal hormones and those of peripheral endocrine glands in the blood plasma of the patients as well as the degree of interrelation of immune and hormone parameters with calculation of the respective correlation coefficients of cortisone and insulin and immunity parameters were investigated to study the state of human adaptation compensation capabilities at demodecosis. Generally accepted clinical and laboratory methods of investigation were used: parasitology, immunology (the parameters of cellular and humoral immunity), hormonal, instrumental and statistical. It was shown that various changes in the concentration of cortisone and insulin occurred at chronic action of invasion as stress, which suggested different types of adaptation reaction, the changes of the regulating influence of adaptive hormones on the factors of immunity in patients with demodecosis, reduction of the strength of correlation and, in a number of cases, changes of its vector. To improve the efficacy of rehabilitation, complex therapy aimed at normalizing hormone level and immunity stimulation is necessary.

Key words: demodecosis, acariosis, invasive dermatozoonosis, diagnosis, prevention.