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№2' 2013
ONCOLOGYInternational Medical Journal, Vol. 19., Iss. 2, 2013, P. 84−88.
ENDOLYMPHATIC, INTRAVENOUS AND INTRA-ARTERIAL CHEMOTHERAPY FOR METASTATIC INOPERABLE GASTRIC CANCER
Donetsk Regional Antitumor Center, Donetsk, Ukraine
Abstract. The purpose of the work was to improve the results of treatment of patients with unresectable metastatic gastric cancer by development and application of methods of regional endarterial and endolymphatic chemotherapy. The results of treatment of 125 patients with the unresectable metastatic gastric cancer aged 32−80 who were treated at DRAC from 2000 to 2009 and received endarterial, intravenous and endolymphatic chemotherapy, were analyzed. Endarterial and endolymphatic chemotherapy were shown to have a few amount of toxic complications. It was proven that endolymphatic chemotherapy was more effective at the mainly metastatic involvement of parietal peritoneum and extraperitoneal lymphatic nodes, while endarterial chemotherapy renders more pronounced effect at presence of metastasis to the liver and pancreas.
Key words: inoperable metastatic cancer of the stomach, endolymphatic chemotherapy, intra−arterial chemotherapy.