Previous Next


№3' 2021


International Medical Journal, Vol. 27., Iss. 3, 2021, P. 60−62.



Vostrotin O. V.

Kharkiv Medical Academy of Postgraduate Education, Ukraine

Stroke remains a global health problem and the second leading cause of death, the main cause of adult disability worldwide. In the provision of medical care for such patients, the emphasis is usually done on the restoration of motor activity, which often pushes into the background disorders in the psycho−emotional and cognitive spheres. By the way, a stroke is the main cause of vascular cognitive dysfunction, that is one of the inhibitory factors in the regeneration of neurological deficits in patients. Many factors and pathophysiological processes play a significant role in the development of these disorders: from the localization and extent of brain injury to the imbalance of monoamine levels in the limbic structures of the central nervous system. To study psychopathological disorders in the patients suffered an ischemic stroke in the right hemisphere of the brain, a search was performed in databases: PubMed, The Cochrane Library, Google Scholar. With the calculation of relative statistical values, the medical records of inpatients and scientific publications on cerebral infarction and neuropsychological disorders, causes, features, manifestations and their impact on the rehabilitation of patients have been analyzed. It is noted that one−third to one−half of stroke patients had psychopathological symptoms. The most common psychoneurological disorders after an acute vascular catastrophe are anxiety−depressive, apathetic−abulic, senestopathic syndromes and the phenomenon of negligence. The redistribution of cases of acute cerebrovascular disorders depending on the type and location of brain damage has been established. Psychopathological syndromes that occur as a result of ischemic stroke in the right hemisphere of the brain: psychoorganic, depressive, asthenic, neurotic syndromes and vascular dementia have been noted.

Key words: psychopathological disorder, depression, apathy, neglect phenomenon, cenestopathy, stroke, examination, meta−analysis.


1. Ryan R. Bailey, Molly Conroy. Diabetes and obesity are associated with disability in community−dwelling stroke survivors: A cross−sectional study of 37,955 behavioral risk factor surveillance system respondents, topics in stroke rehabilitation. 2021. doi: 10.1080/10749357.2021.1904537

2. Phipps M. S., Cronin C. A. Management of acute ischemic stroke // BMJ 2020. № 368. R. l6983. doi:10.1136/bmj.l6983

3. Neurovascular Unit: A critical role in ischemic stroke / L. Wang, X. Xiong, L. Zhang, J. Shen // CNS Neurosci. Ther. 2021. № 27. R. 7−16. URL:

4. For a life free from stroke. World Stroke Organization: website. URL:−

5. Heart disease and stroke statistics−2019 update: A report from the American Heart Association / E. J. Benjamin et al. // Circulation. 2019. Vol. 139 (10). e56−e528. doi:10.1161/CIR.0000000000000659

6. Mechanisms in blood‐brain barrier opening and metabolism‐challenged cerebrovascular ischemia with emphasis on ischemic stroke / S. Sarvari et al. // Metab. Brain Dis. 2020. Vol. 35 (6). P. 851−868. doi:−020−00573−8

7. Secondary prevention and lifestyle indices after stroke in a long−term perspective / A. C. Jonsson et al. // Acta Neurol. Scand. 2018. Vol. 138. P. 227−234. doi:

8. Top 10 research priorities relating to life after stroke − consensus from stroke survivors, caregivers, and health professionals / A. Pollock, B. St George, M. Fenton, L. Firkins // Int. J. Stroke. 2014. Vol. 9. P. 313−320. doi: 10.1111/j.1747−4949.2012.00942.x

9. Stroke survivors' priorities for research related to life after stroke / Ann−Sofie Rudberg et al. // Topics in Stroke Rehabilitation. 2021. Vol. 28 (2). P. 153−158. doi: 10.1080/10749357.2020.1789829

10. "Good outcome" isn't good enough: cognitive impairment, depressive symptoms, and social restrictions in physically recovered stroke patients / A. Kapoor et al. // Stroke. 2017. Vol. 48, № 6. P. 1688−1690. doi:

11. Validation of Cerebral Blood Flow Connectivity as Imaging Prognostic Biomarker on Subcortical Stroke [published online ahead of print, 2021 Mar 28] / C. Wang et al. // J. Neurochem. 2021. doi: 10.1111/jnc.15359

12. Ferro J. M., Caeiro L., Figueira M. L. Neuropsychiatric sequelae of stroke // Nature Reviews Neurology. 2016. № 12. R. 269. doi: 10.1038/nrneurol.2016.46

13. Neuropsychiatric outcomes of stroke / M. L. Hackett, S. Kohler, J. T. O'Brien, G. E. Mead // Lancet Neurology. 2014. № 13 (5). R. 525−534. doi: 10.1016/S1474−4422(14)70016−X

14. Apathy, cognitive impairment, and social support contribute to participation in cognitively demanding activities poststroke / A. Ho, M. L. Nicholas, C. Dagli, L. T. Connor // Behavioural Neurology. 2021. doi: 10.1155/2021/8810632

15. The relationship of psychiatric symptoms with performance−based and self−reported cognitive function after ischemic stroke [published online ahead of print, 2021 Mar 31] / E. Kliem et al. // J. Int. Neuropsychol. Soc. 2021. R. 1−13. doi: 10.1017/S1355617721000187

16. Post−stroke depression: A 2020 updated review / G.C. Medeiros, D. Roy, N. Kontos, S. R. Beach // General Hospital Psychiatry. 2020. № 66. R. 70−80. doi: 10.1016/j.genhosppsych.2020.06.011

17. Study on quantitative diagnosis model of TCM syndromes of post−stroke depression based on combination of disease and syndrome / J. P. Yang et al. // Medicine (Baltimore). 2021. № 100 (12). e25041. doi: 10.1097/MD.0000000000025041

Go on Top