International Medical Journal, Vol. 27., Iss. 3, 2021, P. 60−62.
SYSTEMATIC REVIEW AND META-ANALYSIS OF STROKE-ASSOCIATED PSYCHOPATHOLOGICAL DISORDERS
Kharkiv Medical Academy of Postgraduate Education, Ukraine
Stroke remains a global health problem and the second leading cause of death, the main cause of adult disability worldwide. In the provision of medical care for such patients, the emphasis is usually done on the restoration of motor activity, which often pushes into the background disorders in the psycho−emotional and cognitive spheres. By the way, a stroke is the main cause of vascular cognitive dysfunction, that is one of the inhibitory factors in the regeneration of neurological deficits in patients. Many factors and pathophysiological processes play a significant role in the development of these disorders: from the localization and extent of brain injury to the imbalance of monoamine levels in the limbic structures of the central nervous system. To study psychopathological disorders in the patients suffered an ischemic stroke in the right hemisphere of the brain, a search was performed in databases: PubMed, The Cochrane Library, Google Scholar. With the calculation of relative statistical values, the medical records of inpatients and scientific publications on cerebral infarction and neuropsychological disorders, causes, features, manifestations and their impact on the rehabilitation of patients have been analyzed. It is noted that one−third to one−half of stroke patients had psychopathological symptoms. The most common psychoneurological disorders after an acute vascular catastrophe are anxiety−depressive, apathetic−abulic, senestopathic syndromes and the phenomenon of negligence. The redistribution of cases of acute cerebrovascular disorders depending on the type and location of brain damage has been established. Psychopathological syndromes that occur as a result of ischemic stroke in the right hemisphere of the brain: psychoorganic, depressive, asthenic, neurotic syndromes and vascular dementia have been noted.
Key words: psychopathological disorder, depression, apathy, neglect phenomenon, cenestopathy, stroke, examination, meta−analysis.
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