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№2' 2019

SURGERY

International Medical Journal, Vol. 25., Iss. 2, 2019, P. 27−31.


ANALYSIS OF HEMODYNAMIC RESPONSE AT DIFFERENT REGIMENS OF INFUSION THERAPY IN PATIENTS WITH MODERATE SURGICAL RISK IN ACUTE ABDOMINAL PATHOLOGY


Olha Viktorivna Kravets

State Institution "Dnipropetrovsk Medical Academy of Ministry of Health of Ukraine", Dnipro, Ukraine

Emergency pathology of abdominal organs causes a disordered fluid metabolism. The pathophysiological manifestations of the latter in acute abdominal pathology are a decrease in extracellular space. Volume depletion leads to hemodynamic disturbances and causes a decrease in tissue perfusion, which forms multiorgan dysfunction or failure. In order to assess the effectiveness of the liberal and restrictive regimens of infusion therapy with crystalloid solutions, a comparative analysis of the state of central and peripheral hemodynamics in patients with urgent abdominal organs pathology operated on in the volume of laparotomy was performed. The parameters of central and peripheral hemodynamics were investigated using the method of non−invasive bioelectric rheography. The influence of the infusion therapy volume on the formation of hemodynamic response in patients with urgent abdominal pathology was established. The results of the study enabled to draw the conclusions that the liberal regimen of infusion therapy did not allow a qualitative correction of volume depletion in patients of moderate surgical risk with urgent pathology of abdominal organs due to the formation of hypodynamic type of blood circulation and a disordered tissue perfusion throughout the entire observation period, while restrictive mode, on the contrary, contributes to the correction of volume depletion, supporting the normodynamic type of blood circulation and tissue perfusion during the entire post−surgery period.

Key words: central and peripheral hemodynamics, liberal regimen, restrictive regimen, infusion therapy.


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