ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 24., Iss. 3, 2018, P. 33−36.
DIAGNOSIS AND TREATMENT OF ADOLESCENTS WITH ABNORMAL UTERINE BLEEDING WITH THE ACCOUNT OF VAGINAL BIOCENOSIS CHARACTER
Kharkiv National Medical University, Ukraine
Abnormal uterine bleeding of the pubertal period is a disease associated with functional disorders of the hypothalamic−pituitary−gonadal system and biorhythm disorders during formation of the female reproductive system. Timely diagnosis and adequate treatment play an important role in prevention of the process recurrence, which positively effects development of normal reproductive function in the future. From the age of 14−15 years, vagina microbiocenosis in healthy teenage girls corresponds to the microflora of the vagina of women of reproductive age. Disorders of the normal microbiocenosis of the genital tract depress local immune responses against a background of reduced immunobiological protection. To improve the diagnosis and treatment of this disease, taking into account the study of the microbiological composition of the vaginal secretion, 98 girls−teenagers aged 11−17 were investigated. Bacteriological study of the state of the vaginal microbiocenosis was carried out, the species and quantitative composition of the bacterial vaginal microflora were determined. Microscopy revealed a high number of leukocytes in the vaginal secretion in one of five patients, which indicates the presence of an inflammatory process in the vagina. Bacteriological study against a background of abnormal uterine bleeding demonstrated opportunistic microorganisms, which corresponds to the intermediate type of the biotope of the vagina. To verify the diagnosis, it is advisable to investigate the nature of the vaginal secretion for developing the tactics of complex therapy. As a result of the study, it was found that it is expedient to perform examination and timely correction of the microbiocenosis of the urogenital tract as well as to use probiotics in the treatment regimen to correct the microflora of the vagina.
Key words: uterine bleeding of the pubertal period, vaginal microbiocinosis, probiotics.