International Medical Journal, Vol. 20., Iss. 4, 2014, P. 32−36.
INTERVENTIONAL RADIOLOGY IN DIAGNOSIS AND TREATMENT OF LOCO-REGIONAL PELVIC TUMORS COMPLICATED BY HEMORRHAGE
V. T. Zaytsev Institute of General and Urgent Surgery, NAMS of Ukraine, Kharkiv, Ukraine
Kharkiv Medical Academy for Postgraduate Education, Ukraine
Surgical treatment of patients with locally advanced cancer of the pelvic organs, complicated by bleeding, is one of the challenging problems in urgent oncology. In recent years, to improve the results of surgical treatment in this group of patients with the purpose of hemostasis and impact on the tumor process, transarterial chemoembolization (TACE) of the tumor vessels has been performed. In our work, this method of endovascular treatment was used in 43 patients. Complications and deaths after TACE were not noted. TACE efficacy was controlled with US and CT one month after chemoembolization. Due to TACE of the tumor vessels we managed to control acute arterial hemorrhage in 95.0 % patients, to achieve partial regress or stabilization of the tumor processes and to reduce of tumor size in 32.6 % patients. As the final result of regional chemotherapy we managed to increase the resectability of the locoregional pelvic tumors from 18.6 % to 27.9 %. The survival rate in 31 inoperable patients amounted to 80.6 % within 1 year after TACE; in 12 radically operated patients reached 100 % TACE. Within 2 years the survival rate was respectively 48.4% and 72.7%. Three−year survival was achieved in 4 (36.4 %) of the radically operated patients.
Key words: loco−regional pelvic malignancy, endovascular interventions, chemoembolization of the tumor vessels.