International Medical Journal, Vol. 20., Iss. 4, 2014, P. 14−19.
SIGNIFICANCE OF ST SEGMENT DYNAMIC ASSESSMENT IN ACUTE CORONARY SYNDROME
Penza State University, Medical Institute
N. N. Burdenko Penza Regional Clinical Hospital, Penza, Russia
Coronary artery disease is a leading cause of death worldwide. Owing to the widespread introduction of reperfusion therapy, antiplatelet drugs and methods of secondary prevention, decline in mortality at myocardial infarction with ST segment elevation (STEMI) has been noted. The article presents the findings of clinical studies on the methods evaluating the effectiveness of reperfusion therapy in patients with STEMI, their informativity and availability. The possibility of carrying out daily real−time 12−channel ECG monitoring with analysis of ST segment dynamics as an available non−invasive method, potentially providing reduction in the time of reperfusion effectiveness evaluation is discussed. This allows early selection of high risk patients who are indicated emergency coronary intervention prior to the manifestation of clinical symptoms of ineffective thrombolytic therapy or infarct−related coronary artery rethrombosis after its successful administration.
Key words: acute coronary syndrome, ST segment, thrombolytic therapy, effectiveness of reperfusion, ECG telemetry.