ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 19., Iss. 4, 2013, P. 30−32.
IS HERPES SIMPLEX VIRUS DANGEROUS FOR PREGNANCY?
Kharkiv Regional Clinical Perinatal Centre; Kharkiv National Medical University
Genital herpes simplex virus (HSV) is one of the most common sexually transmitted viral diseases. The infected with HSV woman infects her child in 40% of cases, of them 85% intranatally. The highest probability of HSV infection in the neonatal period is observed at primary infection of the mother the day before the delivery. Neonatal death rate makes 50−70%. The majority of survived have neurological complications, deafness, herpetic lesions of the skin, viral sepsis, encephalitis. The diagnosis is based on the clinical presentation but to prevent transmission early laboratory diagnosis is necessary. Typospecific serological reaction and DNA diagnosis are used. The treatment of primary episode of genital herpes includes systemic antiviral drugs (Acyclovir, Valtrex, Lavomax (Tilirone)), immunomodulators (Cycloferon, Alpharekin, Panavir, Allokin−Alfa), analgesics, antioxidants, vitamins. Acyclovir is also used topically. The pregnant with active eruptions or prodrome signs are performed caesarian section. Breastfeeding is allowed if the breasts are not involved.
Key words: herpes, pregnancy, childbirth, prevention.