International Medical Journal, Vol. 19., Iss. 3, 2013, P. 84−88.
MEASURING OF BLOOD CELL ULTRASTRUCTURE IN THE AREA OF THEIR CONTACT WITH ENDOTHELIUM AT CHRONIC DISEASES OF THE VEINS OF LOWER EXTREMITIES
SI "Institute for General and Urgent Surgery of NAMS of Ukraine", Kharkiv
Abstract. The peculiarities of utrastructural rearrangement of the blood cellular elements interacting with venous endothelium was done using the method of electron microscopy for which endothelial vein wall in the area of the thrombus formation was taken during the operation. The study of ultrastructure of venous blood leucocytes contacting with the pathologically changed vein at chronic diseases of the lower extremities showed that the majority of leucocytes were in metabolically active state. It was established that disorders of cytoplasmic membrane of the leucocytes promoted their fixation on the endothelial surface of the venous wall, separate erythrocytes were destroyed by turbulent motion of the blood. The whole complex of the revealed submicroscopical disorders of leucocytes and erythrocytes in the area of turbulent blood flow at high activity of thrombocytes may promote thrombi formation.
Key words: blood cell ultrastructure, chronic vein diseases, venous insufficiency.