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№1' 2013
PEDIATRICSInternational Medical Journal, Vol. 19., Iss. 1, 2013, P. 27−29.
Optimizing treatment tactics in infants with sepsis
Samarkand State Medical Institute, Republic of Uzbekistan
Abstract. The purpose of the work was to assess the efficacy of combination decontamination of the intestine in treatment of sepsis in infants. Clinical observation was performed on 53 infants (aged 1 month − 1 year) with sepsis. The method of combination intestine decontamination included enterosorption and selective intestine decontamination using oral antibiotic therapy with antibiotics influencing only conventionally pathogenic flora preserving bifido− and lactoflora (gentamicin, canamicin, ercefuril, funistatin). It was shown that the use of combination of decontamination with basic therapy yielded significant reduction of laboratory indices of non−specific endogenous intoxication already on day 10 of treatment and reduced the period of treatment by one week when compared with basic therapy.
Key words: infants, sepsis, combination intestine decontamination.