International Medical Journal, Vol. 25., Iss. 1, 2019, P. 39−42.
COMPARATIVE ANALYSIS OF EFFECT OF ROUX-EN-Y GASTRIC BYPASS AND LAPAROSCOPIC MINI-GASTRIC BYPASS SURGERY ON LIPID METABOLISM IN PATIENTS WITH MORBID OBESITY
SI "O. O. Shalimov National Institute of Surgery and Transplantology" of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
Obesity is associated with elevated morbidity and mortality, one of the causes of those is an increased risk of cardiovascular disease resulted from dyslipidaemia. High levels of triglycerides and low density lipoprotein cholesterol, high density lipoprotein low cholesterol are often found in obese patients. When improving the lipid profile of patients with obesity, the bariatric surgery is effective, however, its results differ significantly depending on the procedure. To study the effect of mini−gastric bypass on lipid metabolism indices in the patients with morbid obesity, the results of treatment of 37 patients, who underwent laparoscopic mini−bypass of the stomach according to R. Rutledge method were retrospectively evaluated. The performed study showed the marked effect of such a surgery on the lipid profile correction in the patients with obesity, i.e. there was a significant decrease in atherogenic and increased antiatherogenic fractions of cholesterol. Reduced levels of triglycerides by 34.8 % and increase in high density lipoproteins by 17.9 % led to a reduced incidence of dyslipidaemia by 29.7 % and, in turn, of cardiovascular diseases.
Key words: lipid metabolism, dyslipidemia, morbid obesity, mini−gastric bypass, Roux−en−Y gastric bypass.