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№1' 2019
OBSTETRICS AND GYNECOLOGYInternational Medical Journal, Vol. 25., Iss. 1, 2019, P. 57−60.
EFFECTIVENESS OF IN VITRO FERTILIZATION IN PATIENTS WITH UNRECOVERED REPRODUCTIVE FUNCTION AFTER LAPAROSCOPIC TREATMENT OF PROGRESSIVE TUBAL PREGNANCY
Kharkiv Mediacl Academy of Postgraduate Education, Ukraine
Tubal−peritoneal infertility, removal of both fallopian tubes, the development of ovarian insufficiency syndrome during the post−surgery period in the patients with tubal pregnancy are indications for in vitro fertilization. The low ovarian response during in vitro fertilization programs is an important issue in modern reproductive medicine. Due to the high frequency and growth trend, as the proportion of "poor responders" among women without tubal ligation and late reproductive age with infertility increases, the efficiency of in vitro fertilization programs decreases. It is known that the use in clinical practice of placental cryoextract during in vitro fertilization programs in women, who have undergone inflammatory diseases of uterus, has contributed to a significant increase in their effectiveness. The purpose of this study was to assess the effectiveness of the recovery of reproductive function in the patients with no effect after laparoscopic treatment of progressive tubal pregnancy, followed by the use of assisted reproductive technologies. In vitro fertilization procedures were used in 181 patients, while in one group they were carried out according to standard technique, in another the patients were preliminarily introduced with 2.0 ml placental cryoextract intramuscularly after 2 days (5 injections). To evaluate the effectiveness of assisted reproductive technologies in the groups of patients the follow−up data of 60 practically healthy women were investigated. A comparative assessment of the results obtained revealed that the use of placental cryoextract as a part of in vitro fertilization protocols contributed to a 1.4−fold increase in advanced uterine pregnancies.
Key words: tubal pregnancy, laparoscopic treatment, placenta cryoextract, in vitro fertilization, reproductive function recovery.