ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 20., Iss. 2, 2014, P. 64−68.
COMPLEX TREATMENT OF ACUTE PELVIC INFLAMMATORY DISEASE IN WOMEN OF REPRODUCTIVE AGE WITH CHRONIC DISEASES OF HEPATOBILIARY SYSTEM
Odessa National Medical University
Odessa Regional Clinical Hospital
Ukrainian Research Institute of Transport Medicine, Odessa
Inflammatory diseases of the pelvic organs are an urgent problem of gynecology. The diseases are caused by complex microbial groups, the treatment requires antibacterial therapy. Treatment with antibiotics in women with chronic diseases of the hepatobiliary system (acalculous cholecystitis, cholangitis, hepatitis) is problematic due to unfavorable effects. Clinical efficacy of an antibacterial drug Zoxicef was investigated in the patients with acute and chronic salpyngooophoritis, pelvioperitonitis, toboovarial inflammatory tumors, and hepatobiliary system pathology. At tuboovarial inflammatory tumors the treatment efficacy is achieved by combination of medication with Zoxicef and laparoscopic surgery in the focus of the inflammation. Side effects were not observed at treatment with Zoxicef (ceftizoxime) did not produce any side effects, allergic reactions. No cases of refusal from treatment were observed. The drug was well tolerated. Three−month follow up did not register any period of exacerbation of hepatobiliary pathology including dyspeptic signs.
Key words: pelvic inflammatory disease, chronic pathology of the hepatobiliary system, Zoxicef (ceftizoxime).