ARCHIVEOBSTETRICS AND GYNECOLOGY
International Medical Journal, Vol. 19., Iss. 3, 2013, P. 65−69.
PERINATAL HYPOXIA AS A CAUSE OF PATHOLOGICAL CHANGES OF ADRENAL GLANDS IN FETUSES AND NEWBORNS
Kharkiv National Medical University
Abstract. Intrauterine fetus hypoxia and asphyxia of the newborn during the delivery in its acute and chronic variants are diagnosed in every fifth newborn weighing 1000 g and more, in particular, in Kharkiv Region this number varied from 16.6 to 21.4% in 2008−2012. The analysis of clinical anatomical peculiarities of lethal cases with perinatal hypoxia vs. histological picture of the adrenals in the newborns showed that in dead fetuses and newborns acute hypoxia (asphyxia) against a background of chronic hypoxia or without was associated with pathological changes in the structure of the adrenals, reflecting development of functional insufficiency. The obtained findings allow to conclude about the necessity of control of adrenals functional state in the mother, fetus and newborn at intrauterine hypoxia and postnatal asphyxia and development of the methods of prevention of adrenal insufficiency development.
Key words: perinatal hypoxia, adrenal glands of the fetuses and newborns.