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№4' 2010

GASTROENTEROLOGY

International Medical Journal, Vol. 16., Iss. 4, 2010, P. 68−72.


Melatonin and gastrointestinal diseases


Oparin A. A., Shapovalova O. E., Dvoyashkina Yu. I., Lavrova N. V.

Kharkiv Medical Academy of Post−graduate Education, Kharkiv, Ukraine

The role of an epiphyseal hormone melatonin in regulation of gastrointestinal tract (GIT) functions both at the local level via endothelial function and secretory−motor processes and the general one via the nervous system and psychosomatic status of the patient is shown. The role of melatonin metabolism in the pathogenesis of main GIT diseases was shown. The unsolved problems associated with this were distinguished.

Key words: melatonin, peptic ulcer, GIT diseases, gastroesophageal reflux disease, mucous membrane.


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