International Medical Journal, Vol. 12., Iss. 1, 2006, P. 79−82.
CORRECTION OF ENDOTHELIUM DYSFUNCTION IN LIMITED SCLERODERMA
Kharkiv Medical Academy of Post−graduate Education, Kharkiv, Ukraine
The effect of hypolipidemia drug Simvastatin on the state of the vascular endothelium and blood lipids in limited scleroderma was studied. The use of Simvastatin in complex treatment of the disease is shown to improve the clinical course of the disease and to allow normalization of the majority of laboratory parameters. The obtained findings suggest pathogenetic substantiation of statins administration in treatment of organic scleroderma.
Key words: limited scleroderma, hypolipidemic therapy, Simvastatin.