International Medical Journal, Vol. 24., Iss. 2, 2018, P. 12−15.
STRUCTURAL AND FUNCTIONAL MYOCARDIAL CHANGES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE COMBINED WITH HYPERTENSION
Kharkiv National Medical University, Ukraine
In modern medicine, combined course of chronic obstructive pulmonary disease and hypertension is an important medical and social problem due to an increase in morbidity, severity of complications, a tendency to increased mortality and loss of working capacity of the patients. Timely prediction of the course of chronic obstructive pulmonary disease, assessment of the future cardiovascular risk, and development of the algorithm for individual prediction of the course of chronic obstructive pulmonary disease with accompanying hypertension on the basis of hemodynamic parameters are necessary. To assess the structural and functional changes in the myocardium in patients with chronic obstructive pulmonary disease in combination with hypertension patients with chronic obstructive pulmonary disease of occupational origin GOLD 2 group B (GOLD 2016) were examined. In one group this disease was accompanied by hypertension. The examination was performed within the period of remission. All patients underwent general clinical and laboratory examination, 6−min walk test, BODE index, pulse oximetry, spirometry, electrocardiography, echocardiography and chest x−ray. The results of this study showed that chronic obstructive pulmonary disease in combination with hypertension is characterized by decreased tolerance to physical activity, a tendency to desaturation during a six−minute walk test and higher values of BODE index. Prognostically unfavorable types of left ventricular geometry and signs of cor pulmonale were more common in patients with a combination of chronic obstructive pulmonary disease and hypertension, which indicates deepening of the processes of remodeling of the left and right parts of the heart and is associated with a high risk of cardiovascular complications.
Key words: chronic obstructive pulmonary disease, hypertension, echocardiography, left ventricle geometry.