International Medical Journal, Vol. 20., Iss. 3, 2014, P. 17−20.
Anomalies of intracerebral and precerebral arteries and their role in ischemic stroke in young adults
M. Gorky Donetsk National Medical University, Ukraine
The study involved 107 patients with an established diagnosis of ischemic stroke aged 34−59 (mean age 47.2±2.6 years). All participants underwent clinical and neurological examination, laboratory, and instrumental studies (MRI and MR−AG of the brain). This allowed to make a group of 77 (72 %) patients aged 34−44 (mean age 36.1±1.7 years) with anomalies of intracerebral (ICAr) and precerebral arteries (PCAr). The data were processed statistically. Among internal carotid artery anomalies full back trifurcation of the right and left internal carotid artery, front trifurcation of the right internal carotid artery, hypoplasia of the right posterior cerebral artery and bilateral hypoplasia of the posterior cerebral artery, aplasia of the posterior communicating artery and the left anterior cerebral artery, hypoplasia of the anterior communicating artery and anterior communicating artery aplasia were determined. The examination of the PCAr found their anomaly in 83.1 % of patients: pathological tortuosity of the internal carotid artery (S−shaped, loop−like, C−shaped), hypoplastic vertebral artery, aplasia of the right vertebral artery. Combination of ICAr and PCAr anomalies was detected in 45.5 % of patients. According to brain MRI in young patients, who suffered ischemic stroke, with abnormalities of cerebral arteries, structural changes in the brain were clarified. Hypoplasia of the right posterior cerebral artery, aplasia of the posterior communicating, left anterior cerebral and anterior communicating artery and pathological S−shaped tortuosity of internal carotid artery, hypoplasia of vertebral artery influence the disease severity.
Key words: ischemic stroke, magnetic resonance angiography, anomalies of intracerebral and precerebral arteries.